Nanomaterials for delivery of medicinal plant extracts and phytochemicals: Potential applications and future perspectives

Nature has been an immense reservoir of therapeutic agents derived from medicinal plants. Bioactive compounds isolated from these plants have demonstrated significant pharmacological potential across a range of medical applications, including cancer therapy, cardiovascular and neuroprotective effects, antimicrobial activity, wound healing, and anti-inflammatory effects. Despite their remarkable therapeutic potential, the clinical translation of these phytochemicals is restricted by challenges such as poor solubility, limited stability, and non-specific distribution. Recent advancements in nanotechnology have revolutionized their delivery by addressing these limitations. Nano-based approaches for delivery of medicinal plant extracts and phytochemicals have emerged as promising strategies in the development of advanced drug delivery systems. This review presents a comprehensive overview of recent progress in nanomaterial-mediated delivery of medicinal plant extracts and phytochemicals, highlighting their transformative potential in overcoming traditional limitations and addressing complex therapeutic needs in modern healthcare.