Khewle, SurbhiSurbhiKhewleDayal, PratyushPratyushDayal2025-08-312025-08-312025-07-1010.1021/acs.jpcb.5c027172-s2.0-105009289610https://d8.irins.org/handle/IITG2025/2806240580147Light-activated polymers (LAPs) are shape-shifting materials capable of transforming their shapes in response to photoinduced chemical reactions, such as cis-trans isomerization and dimerization. Owing to the underlying photochemical reaction, these materials often exhibit behavior analogous to multicomponent/phase polymer blends. In this work, we present a free-energy-based theoretical framework to predict the mechanical behavior of nanoparticle-compatibilized elastic LAP blends that exhibit phase separation. In particular, we incorporate the impact of domain sizes and interfacial areas and establish a criterion for the materials’ susceptibility to mechanical failure under various loading conditions, namely uniaxial and biaxial stretching. Our framework can also be adapted to high-entropy polymers and thermoresponsive or light-activated systems, with potential applications in soft robotics, biomedical devices, micromechanics, 4D printing, and material origami. Additionally, by integrating our model with physics-informed neural networks, we facilitate efficient analysis of complex domain geometries and enable comprehensive parametric studies.falseArticle152052077022-703310 July 20250arJournal0WOS:001519730800001