Pandey, VijayalakshmiVijayalakshmiPandeyRaza, Md KausarMd KausarRazaSonowal, MridupavanMridupavanSonowalGupta, ItiItiGupta2025-08-312025-08-312021-01-0110.1016/j.bioorg.2020.1044672-s2.0-85096432027https://d8.irins.org/handle/IITG2025/2379533223201Donor-Acceptor type BODIPYs with strong absorption and fluorescence in the red region (550–800 nm) are reported. The aromatic groups like N-butylcarbazole/ N-butylphenothiazine/ benzothiadiazole were attached to the C-8 position of the BODIPY core with furan or thiophene spacers. TD-DFT studies indicated significant charge distribution between C-8 aromatic heterocycles and BODIPY core in all the molecules. The in-vitro studies of the N-butylcarbazole substituted BODIPYs indicated significant localization in the endoplasmic reticulum and lysosomes of the cancer cells. The BODIPYs showed decent cytotoxicity after 48 h incubation period (14.9 to 31.8 μM) in HeLa and A549 cancer cells, indicating their potential application as theranostic agents.falseAbsorption | Bioimaging | BODIPY | Carbazole | DFT studies | EmissionArticle10902120January 202122104467arJournal23WOS:000605009100003