Shukla, Ashish KumarAshish KumarShuklaMorya, VinodVinodMoryaDatta, BhaskarBhaskarDatta2025-08-312025-08-312023-10-0210.1039/d3ra05411j2-s2.0-85174567733https://d8.irins.org/handle/IITG2025/26612The ability of bacteria to facilitate fabrication of nanomaterials has been adapted towards bacterial sensing applications. In this work, we fabricate spherical, cubic and truncated octahedron topologies of Cu<inf>2</inf>O nanoparticles via E. coli-facilitated redox reaction in an electrochemical setup. The Cu<inf>2</inf>O nanoparticles exhibit cytochrome c oxidase-like activity with the spherical topology displaying higher catalytic rate compared to the other geometries. The topology-dependent catalytic behavior of Cu<inf>2</inf>O nanoparticles has not been reported previously. The Cu<inf>2</inf>O nanozymes also display E. coli killing activity in a topology-correlated manner. The E. coli mediated redox reaction in an electrochemical setup is being reported for the first time for synthesis of different topologies of Cu<inf>2</inf>O which also exert a variable antibacterial effect.trueArticlehttps://pubs.rsc.org/en/content/articlepdf/2023/ra/d3ra05411j2046206928767-287722 October 20233arJournal4WOS:001075646800001