Ghosh, SubhojitSubhojitGhoshSolanki, RaghuRaghuSolankiBhatia, DhirajDhirajBhatiaSankaranarayanan, SubramanianSubramanianSankaranarayanan2025-08-312025-08-312025-05-0110.1016/j.plana.2025.1001612-s2.0-105005791399https://d8.irins.org/handle/IITG2025/28144Nature has been an immense reservoir of therapeutic agents derived from medicinal plants. Bioactive compounds isolated from these plants have demonstrated significant pharmacological potential across a range of medical applications, including cancer therapy, cardiovascular and neuroprotective effects, antimicrobial activity, wound healing, and anti-inflammatory effects. Despite their remarkable therapeutic potential, the clinical translation of these phytochemicals is restricted by challenges such as poor solubility, limited stability, and non-specific distribution. Recent advancements in nanotechnology have revolutionized their delivery by addressing these limitations. Nano-based approaches for delivery of medicinal plant extracts and phytochemicals have emerged as promising strategies in the development of advanced drug delivery systems. This review presents a comprehensive overview of recent progress in nanomaterial-mediated delivery of medicinal plant extracts and phytochemicals, highlighting their transformative potential in overcoming traditional limitations and addressing complex therapeutic needs in modern healthcare.falseBioactive compounds | Medicinal Plants | Nanomedicine | Nanotechnology | PhytochemicalsReviewhttps://doi.org/10.1016/j.plana.2025.10016127731111May 20251100161reJournal1