Appayee, ChandrakumarKumar, AmitAmitKumar2025-09-042025-09-042016-01-01https://d8.irins.org/handle/IITG2025/31734We report a concise method for the formal synthesis of trisubstituted γ-butyrolactone by cross aldol reaction of commercial available aldehyde and -chlorohexanal in presence of chiral amino acid based organocatalyst. We have synthesized -chlorohexanal by -chlorination of hexanal by using a chiral catalyst. After three steps, we will reach to our final goal which is the biologically active (-)-Phaseolinic acid. We had started our synthesis from γ-butyrolactone which is very cheap and easily available.col.; ill.; 30 cm.Short and effective asymmetric synthesis towards alky-lated paraconic acids through organocatalysisM.Sc.23p.M.Sc.123456789/380