Saha, SarmisthaSarmisthaSahaMishra, AbhijitAbhijitMishra2025-08-312025-08-312022-09-2610.1039/d2bm01295b2-s2.0-85141023117https://d8.irins.org/handle/IITG2025/2592636193822We developed a strategy to use lysozyme (Lys) as a template to produce mesoporous zeolitic imidazolate framework (ZIF-8) structures under physiological conditions. Thereafter, an amphiphilic triblock copolymer, PEG-PPG-PEG, was used to form protective core-shell ZIF-8 nanocomposite coatings to protect the encapsulated drug epigallocatechin-3-gallate (EGCG), to achieve notable antibacterial properties against E. coli, S. aureus and MRSA strains. Moreover, nanocomposites exhibited anti-inflammatory activity by counteracting the secretion of cytokines in THP-1 macrophages.falseArticle20474849481-48826 September 20226arJournal5WOS:000863713900001