Ghosh, PayelPayelGhoshPraneeth, N. V.S.N. V.S.PraneethJoshi, GayatriGayatriJoshiChakraborty, Arup LalArup LalChakrabortyChoudhury, Sharmistha DuttaSharmistha DuttaChoudhurySai, Vv RaghavendraVv RaghavendraSaiKhatua, SaumyakantiSaumyakantiKhatua2025-08-312025-08-312024-01-01[9798350395136]10.1109/BioSensors61405.2024.107127092-s2.0-85208095998https://d8.irins.org/handle/IITG2025/29225The development and characterization of a biosensing platform utilizing chemically synthesized gold triangular nanoprisms is reported. These nanoprisms are specially designed to have stable deposition on a glass substrate with plasmon resonances tuned to visible-NIR wavelengths. The biosensing protocol of DNA-RNA hybridization is utilized by tagging these nanoprisms with a complementary sequence of DNA achieving specific detection of the targeted complementary miRNA. A nanoprisms-coated glass substrate having sensitivity around 300 nm/RIU has been used to detect ultralow concentrations up to 100fM of miRNA of 25 base-pair sequences. The sensing activity is further extended to nanoprisms deposited u-bent optical fiber probes that not only contribute robustness to the system but also characterization shows higher sensitivity up to 600 nm/RIU.falseOptical Fiber Sensor | Surface Plasmon ResonanceConference Paper20240cpConference Proceeding0