Promising drug targets and associated therapeutic interventions in Parkinson's disease
Source
Neural Regeneration Research
ISSN
16735374
Date Issued
2021-09-01
Author(s)
Rai, Sachchida Nand
Singh, Payal
Varshney, Ritu
Chaturvedi, Vivek K.
Vamanu, Emanuel
Singh, M. P.
Singh, Brijesh Kumar
Abstract
Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious and etiological treatment is required. In this review, we have compiled the information covering limitations of current therapeutic options in PD, novel drug targets for PD, and finally, the role of some critical beneficial natural products to control the progression of PD.
Subjects
dopamine | epigenetics | gene therapies | glutamate receptor | levodopa | molecular chaperones | monoamine oxidase B | mucuna alpha-synuclein | Parkinson's disease | striatum | substantia nigra
