Polystyrene-Supported Aminocatalyst Derived from Diarylprolinol for Asymmetric α-Amination of Aldehydes

A new class of polystyrene-supported aminocatalysts with a triazole linker from diphenyl prolinol were developed. Their catalytic activity was tested in the asymmetric α-amination of aldehydes. The substrate scope of this catalysis was studied under the optimized reaction conditions. The reusability of the polystyrene-supported aminocatalyst was demonstrated up to four cycles. Based on the reaction results, a reaction mechanism was proposed for the asymmetric α-amination of aldehydes.